1ap-diphenol: oxygen In the sequence, assays using mixtures of the inhibitory compounds at a concentration of 12.5% of their IC50 value were performed to evaluate the combined effect of the inhibitors on the strain growth. Notes Keep container tightly closed in a dry and well-ventilated place. For obtaining a higher solubility , please warm the tube at 37 and shake it in the . Xiang, Q., and Lee, Y. Syringaldehyde. Biomed Pharmacother. Boerjan, W., et al (2003). It is soluble in water and insoluble in most organic solvents. It possesses worthy bioactive properties and is, therefore, used in pharmaceuticals, food, cosmetics, textiles, pulp and paper industries, and even in biological control applications. 4-Hydroxy-3,5-dimethoxybenzaldehyde has an alcoholic odor, light yellow-green to brown crystalline powder, Reported found in pineapple, beer, wine, grape brandy, rum, many different whisky products, sherry, roasted 130.120.0 C. It has been reported to be used as a mediator in the degradation of indigo carmine by bacterial laccase (benzenediol oxygen oxidoreducase) obtained from the organism -Proteobacterium JB[18]. Third group receives vehicle for a period of 21 days and then ISO (100mg/kg, s.c.) on 20th and 21st day at an interval of 24h. Fourth group is given Syringaldehyde for 21 days at 12.5mg/kg, p.o. Content Brief. You will hear from us soon. A simple and sensitive spectrophotometric method was developed for kinetic determination of amino acids through their condensation with syringaldehyde. These materials can be generated from a renewable phenol (syringaldehyde) that can be derived from lignocellulosic biomass. Got it. Although this practice is not common for the recovery of syringaldehyde, it is slowly emerging, since value-added products from wastes offer a promising future. We will send it to your Email address shortly. Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 g/mL Stanikunaite R, et al. (2001). You may receive emails regarding this submission. Laccase Laccase (p-diphenol: oxygen oxidoreductase, EC 1.10.3.2) is a copper-containing oxidase, and was first discovered in the Japanese lacquer tree in 1883. Cyclooxygenase-2 inhibitory and antioxidant compounds from the truffle Elaphomyces granulatus. Lignin also provides plants with a vascular system for the conveyance of water and solutes[8]. The major final application of these lignins is as dispersant: the use of sulfomethylated kraft lignin was patented in 1954 [ 37 ]. Anti-hyperglycemic and anti-inflammatory activities [1]. The sixth group is treated with 50mg/kg of Syringaldehyde for 21 days and ISO on 20th and 21st day. Based on 1 publication(s) in Google Scholar. The carbon atoms in the chemical structure of SYRINGALDEHYDE are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated - each carbon atom is considered to be associated with enough hydrogen atoms to provide the . Shop Syringaldehyde, 98+%, Thermo Scientific at Fishersci.co.uk. 3. Syringaldehyde, or 3,5-dimethoxy-4-hydroxybenzaldehyde, is a naturally occurring unique compound with assorted bioactive characteristics that belongs to the phenolic aldehyde family. Years of tedious research have led to the current development and understanding of the synthesis of the syringyl unit in plants. Some species of insects use syringaldehyde in their chemical communication systems. Syringaldehyde is also used as a mediator in laccase-assisted biobleaching processes. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Li, L., et al (2001) Plant Cell 13(7), 1567-1586. Despite the fact that the fate of lignin ends at a bio-fuel refinery[6], its hidden wealth can be extracted prior to its conversion into biomass feedstock. Shop Syringaldehyde, 98+%, Thermo Scientific at Fishersci.no. Click Here to Find How Many Items You Have Added:), A polyphenol with diverse biological activities, Tel: (626) 353-8530 A. Syringaldehyde is produced naturally by many plants, including peanuts, soybeans, and vanilla beans. Syringaldehyde showed a significant decrease in natural mobility by the 4th day and caused significant mortality on the 8th day. By weight, the total yield of bisulfite soluble material was 42.9%, while the yield of total carboxyl-containing constituents of the . [5] Its presence in the ancient Egyptian drink shedeh could confirm it was made out of grape, as syringic acid is released by the breakdown of the compound malvidin, also found in red wine. Syringaldehyde. Solubility: Acetone or DMF Storage conditions: Store in a cool, dry place Also known as 3,5-Dimethoxy-4-hydroxybenzaldehyde . , T: c10h16n2o2, : The best yields in syringaldehyde and lignin from organosolv lignin were reported in a microwave-heated 2M NaOH solution by using hydrogen peroxide as the oxidant and La-SBA-15 as the catalyst [78]. Sorry, but the email address you supplied was invalid. Syringic Aldehyde, 3,5-DiMethoxy-4-hydroxybenzaldehyde SynonyMs 4-Hydroxy-3,5-diMethoxybenzaldehyde, Syringaldehyde Vetec(TM) reagent grade, 98%, 3,5-Dimethoxy-4-hydroxybenzaldehyde for synthesis, 4-Hydroxy-3,5-dimethoxybenzaldehyde (syringaldehyde), Syringaldehyde (4-Hydroxy-3,5-Dimethoxybenzaldehyde 98%, Hot Sell Chemical Pharmaceutical Intermediate Syringaldehyde CAS 134-96-3, 4049 | 4-HYDROXY-3,5,-DIMETHOXY BENZALDEHYDE, Benzaldehyde, 4-hydroxy-3,5-dimethoxy-(134-96-3), P261-P264-P271-P280-P302+P352-P305+P351+P338, 4-Hydroxy-3,5-dimethoxybenzaldehyde azine, 8-(DIETHYLAMINO)OCTYL 3,4,5-TRIMETHOXYBENZOATE HYDROCHLORIDE, diethyl (3,4,5-trimethoxybenzoyl)malonate, 4-ETHOXYCARBONYLOXY-3,5-DIMETHOXYBENZOIC ACID, Keep in dark place,Sealed in dry,Room Temperature. 2. Anti-hyper For the best experience on our site, be sure to turn on Javascript in your browser. Applications Products Services Support. Molecular Formula C 9 H 10 O 4; Average mass 182.173 Da; Monoisotopic mass 182.057907 Da; ChemSpider ID 8333; More details: . Chat now for more business. During the experimental procedure body weight of animals are monitored and on 22nd day, 24h after second injection of ISO, rats sre sacrificed by cervical decapitation.Note: Body weight of animals belonging to different groups did not differed significantly but heart weight of ISO challenged animals were highly elevated (p0.05) than control rats. . Being the second most copious biopolymer only to cellulose, lignin offers a continuous, renewable, and cheap supply of syringaldehyde. Please note that all emails sent by OKCHEM are from ***@okchem.com, service@mail. Commercial kraft lignins are usually modified to their increase it solubility in aqueous solutions by means of oxidative sulfonation, carboxylation, and sulfomethylation. Syringaldehyde is a promising aromatic aldehyde that no longer deserves to remain in obscurity. dimethyxybenzaldehyde. (2012)[15] studied the effects of non-leachable low molecular weight phenols with lactase on unbleached flax fibers in producing bio-modified pulp and paper. Phytother Res. syringaldehyde solubility. Antibodies & Protein Biology Antibody Production & Purification Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 g/mL[2]. Moreover, the bio-origin of this compound has not been adequately reviewed. Regnault-Roger, C., et al (2004). : 134-96-3; Synonyms: 3,5-Dimethoxy-4-hydroxybenzaldehyde; 4-Hydroxy-3,5-dimethoxybenzaldehyde; Linear Formula: HOC6H2(OCH3 . Anti-hyperglycemic and anti-inflammatory activities. Isolated from Pisonia aculeata and Panax japonicus var. Target-Focused Phenotypic Screening Library, Nonsteroidal Anti-Inflammatory Compound Library, Anti-Inflammatory Traditional Chinese Medicine Compound Library. Name:3,5-Dimethoxy-4-hydroxybenzaldehyde,CAS:134-96-3.Molecular Fomula:C9H10O4,Molar Mass:182.173,Density:1.234g/cm 3 ,Melting Point:110-113,Boling Point:322.1C . Fascinatingly, in angiosperms, these fiber cells are mainly composed of S-lignin. 2009 Apr;23(4):575-8. Linear Formula: HOC 6 H 2 (OCH 3) 2 CHO. National Center for Biotechnology Information. **When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online). All of the co-solvents are available by MCE. Email: sales@glpbio.com. The genes involved in S-lignin synthesis developed much later than G-lignin, rendering evidence of evolution from softwood plants (gymnosperms) to hardwood plants (angiosperms)[11]. Anti-hyperglycemic and anti-inflammatory activities[1]. 19.713mg, V1C1C2V2, Tocris INSOLUBILITY in water MOLECULAR WEIGHT 182.1756 SOLUBILITY alcohol NOTES FEMA# 4049 CLASS Flavor and Fragrance Chemical Compounds Get A Quick Quote For more information call 1-800-282-3982 or email info@parchem.com! Kleinert, M., and Barth, T. (2008). Boundagidou, O. G., et al (2010). Journal of Stored Products Research 40(4), 395-408. Syringaldehyde quantity + Add to . Here's Arctander talking about its scent: "Sweet, balsamic-floral odor of considerable tenacity. Rouche, H.-L. (1978). Anti-hyperglycemic and anti-inflammatory activities[1]. All of the above co-solvents are available for purchase on the GlpBio website. Any emails will include the ability to opt-out of future communications. It is a colorless liquid that has a characteristic floral odor. INDOFINE Chemical Company supplies SYRINGALDEHYDE for pharmaceutical, agricultural and life science industries. ; for 21 daysAdult male albino wistar rats are randomly divided into six groups (n=6), first group serves as control and receives vehicle (orally) for 21 days. Syringic acid can be found in several fruits including olives, dates, spices, pumpkin, grapes, [3] acai palm, [4] honey, red wine, among others. All of the above co-solvents are available for purchase on the GlpBio website. The topic is also known as: Gallaldehyde 3,5-dimethyl ether & 4-hydroxy-3,5-dimethoxybenzaldehyde. InChl Key. Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehyde is an organic compound with the molecular formula CHCHO. In these processes, synthetic mediators such as HBT, violuric acid, and promazine were used. 2.1. Room temperature in continental US; may vary elsewhere. Shop Syringaldehyde, 98+%, Thermo Scientific at Fishersci.nl. Phytother Res. Evaluation sample solution : ship with blue ice. [16] The use of syringaldehyde as a precursor to composites has the potential to reduce the cost and environmental impact of structural materials, while meeting or exceeding the performance of . Environmental Science & Technology 40(24), 7811-7819. [1]. Trends in Food Science & Technology 15, 191-200. C10H16N2O2 Assessment of Total Phenolic Content (TPC) and Total Flavonoids Content (TFC) The TPC can mirror the antioxidant potential of plant extracts [].The TPC of ART, calculated as gallic acid equivalent (R 2 = 0.9941), was 44.87 1.88 g GAE/mg dry extract, well above the TPC previously reported in artichoke bracts and whole inflorescence crude extracts and comparable to artichoke stems [10,17]. 151, 3. . Syringaldehyde has been reported to be separated and analyzed via a recrystallization process. Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Please contact us first if there is no in vivo formulation at the solubility Section. Solubility. Please make sure the liquid is clear before adding the next solvent. From our knowledge this is the most detailed study presenting the enzymatic degradation of . Note: Body weight of animals belonging to different groups did not differed significantly but heart weight of ISO challenged animals were highly elevated (p0.05) than control rats. Cyclooxygenase-2 inhibitory and antioxidant compounds from the truffle Elaphomyces granulatus. 98%, FG. We do not sell to patients. HS Code Reference . Phytother Res. Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 g/mL. Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. ChEBI ID. Shop Syringaldehyde, 98+%, Thermo Scientific at Fishersci.be. Syringaldehyde has powerful antioxidant activity, in minimizing DNA damage, and activating survival signal Akt . If you have published this work, please enter the PubMed ID. When the particle size of the powder was controlled to be 50 mesh, the effects of temperatures (40, 45, 50, 55, and 60 C), pressures (15, 20, 25, 30, and 35 MPa), concentrations of . The study ascertained that syringaldehyde was able to increase the degradation of indigo carmine by 57%. According to their study, the dimethoxy substitution in syringaldehyde as well as its syringol moiety was acknowledged for exhibiting enhanced antioxidant properties[14]. Contact China Trader BIC-CHEM KANGMING PHARMA INDUSTRIES for the product SYRINGALDEHYDE. Solubility Very sparingly soluble in water. 2018 Dec;108:625-633. []10milliliter They are for reference only. Definitions of Syringaldehyde, synonyms, antonyms, derivatives of Syringaldehyde, analogical dictionary of Syringaldehyde (English) Syringaldehyde is very similar in structure to its infamous counterpart, vanillin, and it has comparable applications[3]. Products. . It is soluble in alcohol and organic solvents. 1u(1u1211/12 Another research focused on potentially cost-effective ligninderived natural mediators, including syringaldehyde obtained from spent pulping liquors and plant materials used in the paper pulp laccase-mediator delignification process in combination with peroxide bleaching[17]. InChl . Applied Geochemistry 17, 129-162. It becomes more useful in producing phenolic aldehydes when the lignin is subjected to fewer transformations or chemical treatments. In the nature, it is found easily in the bark of Maple and Spruce trees. Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 g/mL. Your information is safe with us.Privacy Policy. Biological control activity Creighton, R. H. J., et al (1941). An investigation utilizing spectrophotometric analysis to determine amino acids using syringaldehyde was also reported [22]. Shahzad S, et al. : Method for preparing in vivo formulation: Take L DMSO master liquid, next addL PEG300, mix and clarify, next addL Tween 80, mix and clarify, next add L ddH2O, mix and clarify. Only preliminary in vitro tests have been reported in most cases, but a new potential research area and application of syringaldehyde has been identified. [2], Syringic acid can be found in several fruits including olives, dates, spices, pumpkin, grapes,[3] acai palm,[4] honey, red wine, among others. MW197.13 1 The typical laccase molecular structure (6.5 nm 5.5 nm 4.5 nm) generally contains about 500-550 amino acids with molecular weights of about 50-130 kDa (Fig. Be sure to add the solvent(s) in order. Syringaldehyde exerts anti-hyperglycemic effect in rat model of diabetes induced by streptozotocin. Syringaldehyde and ABTS showed as the best redox mediators allowing the highest transformation yields (50-100%) in less than 3 h. However, there is not a broad spectrum mediator since carbamazepine was not transformed by any laccase-mediator system. Research demonstrated that Arabidopsis mutants were no longer upright since they lacked lignified interfascicular fibers, providing evidence that macro-metabolite lignin is responsible for the structural integrity of plants. TargetMol Shahzad S, et al. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving. The ever-increasing safety concerns over synthetic antioxidants and the harmful side effects of chemo-therapeutic drugs, coupled with their high costs[1], have created a new path for the development of cheaper, sustainable, and most crucially, natural anti-oxidants, drugs, and food additives[2]. VP: 0.000478 mm Hg (25 deg C, Mod-Grain method) Water Solubility Estimate from Log Kow (WSKOW v1.41): Water Solubility at 25 deg C (mg/L): 9526 log Kow used: 0.88 (estimated) no-melting pt equation used . US EN. JavaScript seems to be disabled in your browser. Vergnenegre, A. Aroma characteristics at 1.0%: weak sweet, slightly smoky, cinnamic, vanilla, leather-like with a phenolic It exhibits antioxidant activity and is reported to inhibit prostaglandin synthetase enzyme. Figure 1 the chemical structure of syringaldehyde. SYNTHESIS: (from protocatechualdehyde) A solution of 18 g commercial protocatechualdehyde (3,4-dihydroxybenzaldehyde) in 200 mL warm acetic acid was filtered free of any insolubles, to provide a very dark but clear solution. Syringaldehyde inhibits COX-2 activity in a dosedependent manner with an IC50 of 3.5 g/mL[2]. Phenolic compounds (like syringaldehyde), which are obtained from lignin pyrolysis in vegetation, have been proposed as tracers specific for plant taxonomy. * Please select Quantity before adding items. A study on the insecticidal properties of syringaldehyde was carried out on Acanthoscelides obtectus beetles[21]. 100 microliter (0.1 ml) , . The population of Klebsiella pneumonia was reduced to 61% by syringaldehyde, whereas acetosyringone gave a major reduction up to 99%. Please be alert of other emails sent to you in the name of OKCHEM. [2]. [1]. Miguel Carrero Glvez, Carmelo Garca Barroso and Juan Antonio Prez-Bustamante, Zeitschrift fr Lebensmitteluntersuhung und -Forschung A, Volume 199, Number 1, pages 2931, "Phytotoxic Activity and Identification of Phytotoxic Substances from Schumannianthus dichotomus", "The synthesis of certain pyrogallol ethers, including a new acetophenetide derived from the ethyl ether of syringic acid", "Syringic acid (SA) A Review of Its Occurrence, Biosynthesis, Pharmacological and Industrial Importance", https://en.wikipedia.org/w/index.php?title=Syringic_acid&oldid=1064224487, This page was last edited on 7 January 2022, at 07:35. [5] Its presence in the ancient Egyptian drink shedeh could confirm it was made out of grape, as syringic acid is released by the breakdown of the compound malvidin, also found in red wine. It can also be synthesized artificially. Jinan Future Chemical Industry Co.,Ltd +86 531 68657995 +86 13280017993; sales@bosschemical.com; HOME; Products. All Photos (1) W404926. Skip to content. All rights reserved, 3,5-Dimethoxy-4-hydroxybenzaldehyde~4-Hydroxy-3,5-dimethoxybenzaldehyde, Syringaldehyde (4-Hydroxy 3,5-dimethoxybenzaldehyde), 3,5-dimethoxy-4-hydroxybenzaldehydesyringaldehyde, SYRINGALDEHYDE (3,5-DIMETHOXY-4-HYDROXYBENZALDEHYDE), Syringaldehyde,3,5-Dimethoxy-4-hydroxybenzaldehyde, 4-Hydroxy-3,5-dimethoxybenzaldehyde, 3,5-DIMETHOXY-4-HYDROXYBENZALDEHYDE, PURE, 3,5-DiMethoxy-4-hydroxybenzaldehyde, 98% 25GR, 3,5-Dimethoxy-4-hydroxybenzaldehyde These vessels are mainly composed of G-lignin and do not contain S-lignin since the enzymatic genes that encode for sinapyl alcohol are lacking in gymnosperms[9]. Enzyme and Microbial Technology 41, 794-799. We're doing our best to keep everyone healthy and safe in the workplace while also avoiding the interruptions to our day-to-day operations. Fifth group receives Syringaldehyde at concentration of 25mg/kg, p.o. 2018 Dec;108:625-633. Syringaldehyde may be used as an analytical reference standard for the determination of the analyte in guacoextracts and pharmaceutical preparations,(1) cognacs and wines,(2) plum brandies,(4) and wheat straw(5) by various chromatography techniques. Spectrochimica Acta Part A.: Molecular and Biomolecular Spectroscopy, 54(2), 359-365. The persimmon pulp was dis - Hacke, U. G., and Sperry, J. S. (2001). In order to appreciate the complexity and diversity of nature and her unique attributes, it is vital to know how the syringyl unit comes into existence in lignin. Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis [1]. barley and hardwood smoke. syringaldehyde 134-96-3_OKCHEM. view and buy high purity Syringaldehyde from AOBIOUS, the leading supplier of life science reagents In the food industry there is also a tendency to utilize naturally occurring flavor compounds that exhibit antioxidant and antimicrobial properties, hence providing a potential source of nonsynthetic preservatives and additives. DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml,Ethanol: 1 mg/ml. RID/ADR. Simoneit, B. R. T. (2002). The 2D chemical structure image of SYRINGALDEHYDE is also called skeletal formula, which is the standard notation for organic molecules. Lignin being an amorphous heteropolymer, the elucidation of its biosynthetic pathway is not an easy task. Your information is safe with us. []10millimolar Syringaldehyde is a naturally occurring organic compound. 12.5mg/kg, 25mg/kg, and 50mg/kg; p.o. This value decreased in the order from syringaldehyde > protocatechuic aldehyde > vanillin. Compound Syringaldehydewith free spectra: 12 NMR, 9 FTIR, 1 Raman, and 15 MS. Garrote, G., et al (2004). An excellent natural source of syringaldehyde lies within the cell walls of plants. molar weight1g/mol. A study related to the structural motifs of syringaldehyde and other benzaldehydes for their antioxidant capabilities was approached by[14]. as the oxygen concentration in the biosphere increases due to the action of cyanobacteria, which started releasing photosynthetic oxygen to the earth's atmosphere about 2.45 billion years ago, the widely available and water soluble feii (ferrous ion) gradually oxidizes to feiii (ferric ion) with practically no solubility in water and very limited (1998). " The SYRINGALDEHYDE molecule consists of 10 Hydrogen atom(s), 9 Carbon atom(s) and 4 Oxygen atom(s) - a total of 23 atom(s). Syringaldehyde is widely used as a molecular marker for biomass smoke from aerosol particulate matter, namely to monitor pollution sources and detect the extent of combustion[19]. However, treatment of rats with Syringaldehyde significantly reduced heart weight in dose dependent way. [2]. Cyclooxygenase-2 inhibitory and antioxidant compounds from the truffle Elaphomyces granulatus. Syringaldehyde is a(n) research topic. It is sensitive to air. In this study, we performed a postprandial glucose test (in vivo) including oral glucose tolerance test (OGTT) and oral starch tolerance test (OSTT) in fructose-induced diabetic mice on a high-fat diet for mimicking type 2 diabetes to explore the hypoglycemic . Organic markers in wood smoke The initial soluble solid content of the pulp was determined to be 18.2 1.0 Brix. 3-Hydroxybenzaldehyde | C7H6O2 | CID 101 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . (2001). for 21 days and ISO on 20th and 21st day. ; for 21 days US Patent 4,115,650. 2018 Dec;108:625-633. Chat now for more business. 1. Apart from antioxidant capability, Syringaldehyde also has anti-inflammatory activity as it is found to have inhibitory action on cyclo-oxygenase 2 (COX-2) in mouse macrophage cell line[1]. Syringaldehyde is used in biological studies for the isolation and structural characterization of milled wood lignin, dioxane lignin, and cellulolytic lignin preparation from Brewer''s spent grain. Anti-hyperglycemic and anti-inflammatory activities. The molecular weight of SYRINGALDEHYDE is determined by the sum of the atomic weights of each constituent element multiplied by the number of atoms, which is calculated to be: This provides an additional option in the analysis of amino acids with advantages of reagent availability, reagent stability, and less time consumption. Syringaldehyde seems to play a key role in the detection of hardwood smoke. Antibodies & Protein Biology Antibody Production & Purification Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 g/mL. For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 for several months. Because G-lignin is lacking in angiosperms, additional specialized cells referred to as fiber cells provide much needed mechanical support[10]. Shop Syringaldehyde, 98+%, Thermo Scientific at Fishersci.ca.
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