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Pfizer (PFE) to Buy Arena, Boost Immuno-Inflammatory Pipeline Its bipartisan, urgent, and inevitable. S&P 500 earnings estimates for 2023 take complete U-turn as recession risks loom, according to BofA. Olorinab is targeting pain management for two indications, irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Intended to be a once-daily oral therapy targeting sphingosine-1-phosphate (S1P) receptor modulator to provide systemic and local cell modulation, etrasimod is being tried for immune and inflammatory-mediated diseases such as ulcerative colitis, Crohns disease, and atopic dermatitis, the three current indications being developed by Arena. Pfizer is reportedly pursuing the acquisition in order to expand its scope of. The company also has two other yet undisclosed G proteincoupled receptor (GPCR) based therapies in early pre-clinical evaluations with collaboration agreements for development. The trial is expected to evaluate the effects of etrasimod, 1mg and 2mg dosage levels, versus placebo on multiple efficacy measures including a 3-component Mayo Score, total Mayo Score (TMS), clinical remission and clinical response in up to 160 patients. by When the symbol you want to add appears, add it to Watchlist by selecting it and pressing Enter/Return. In addition, Arena's pipeline includes two development-stage cardiovascular assets, temanogrel and APD418. Arena (ARNA) Starts Phase II Study on Coronary Drug Temanogrel argenx | Pipeline - Differentiated Immunology Solutions While the rest of 2019 will be muted in terms of data releases, 2020 will likely see at least one readout, and possibly an update on ralinepag (depending on United Therapeutics timeline). Arena Pharmaceuticals | CipherBio Arena is also entitled to potential milestone payments of up to $400 million based on the achievement of certain regulatory events as well as low double-digit tiered royalties on annual net sales of ralinepag products. Under the terms of the agreement, Pfizer will acquire all the outstanding shares of Arena for USD100 per share in an all-cash transaction for a total equity . MLR-US-NP-0004v1.0 05/21. The core of its cannabis operation consists of Olorinab (APD371), an investigational, oral, full agonist of the cannabinoid type 2 receptor (CB2), which aims to treat patients with diseases . Dec. 13 analyst call on its Arena Pharma acquisition focused primarily on etrasimod, currently in Phase 2 and 3 trials as a treatment for the chronic inflammatory bowel disease ulcerative colitis. The company is advancing the candidate to a phase III registrational program to evaluate it as a potential treatment for atopic dermatitis. This contains focused and comprehensive coverage of pharmaceuticals in development, an exhaustive resource for the users. Federal cannabis legalization might reduce conventional pharmaceutical sales by billions of dollars according to a new study conducted by researchers from . On July 25th, Arena announced the first subject doses in CAPTIVATE Phase IIb trial for IBS, evaluating three dose levels over a twelve-week period in approximately 240 patients with various IBS-related symptoms. The mortality rate remains high as DHF is a complex disease; it is also the leading cause of hospitalization for those over 65 years of age. Identify which of Arena Pharmaceuticals Incs products will be commercialized, helping you to better contend with shifting product portfolios, and allowing you to stay one step ahead of the market. Arena (ARNA) Stock Up in 6 Months on PFE Merger Deal & Pipeline - Yahoo! ARNA stock rose more than 83% after Pfizer announced that it was acquiring Arena Pharmaceuticals at a price of $100 per share. Pfizer concludes Arena Pharmaceuticals acquisition for $6.7bn Arena Pharmaceuticals, Inc. - Product Pipeline Review - 2014 is a new market research publication announced by Reportstack. Pfizer has agreed to acquire Arena Pharmaceuticals for approximately $6.7 billion, the companies said today, in a deal designed to expand the buyer's immuno-inflammatory disease pipeline, led by . Type a symbol or company name. Meanwhile, the company is developing its lead pipeline candidate, etrasimod, for multiple indications. As of March 31st, Arena had $1.1B in cash, including United Therapeutics payment, with over $400M in milestone payments expected in the future. (SPACs), Transportation, Infrastructure & Logistics, Dravet Syndrome (Severe Myoclonic Epilepsy of Infancy). Please note that the candidate enjoys Fast Track designation in the United States for cMVO. United Therapeutics Announces Closing Of License Agreement With Arena /PRNewswire/ -- Arena Pharmaceuticals, Inc. (NASDAQ: ARNA) today announced a strategic shifting of priorities to emphasize its proprietary clinical stage. In addition, Arena's pipeline includes two development-stage cardiovascular assets, temanogrel and APD418. Arena's Pipeline Holds Promise, Plunging Revenues a Concern Our Development Pipeline. However, a mid-stage study evaluating the companys another key pipeline candidate, olorinab, in abdominal pain due to irritable bowel syndrome failed in March. Arena Pharmaceuticals, Inc. ARNA announced that it has dosed first patients in a phase II study to evaluate its key pipeline candidate etrasimod as a potential treatment for moderate-to . ARENA Pharmaceuticals is a team with a singular purpose - deliver our important medicines to patients. Contact Us USA 6154 Nancy Ridge Drive, San Diego, CA 92121 One Beacon Street, Floor 28 . Pfizer Acquires Arena Pharmaceuticals To Widen Immuno-Inflammatory When administration was discontinued, lymphocyte levels either increased back towards the baseline, or returned to original levels. This report provides an overview of the Arena Pharmaceuticals, Inc.'s pharmaceutical research and development focus. Some better-ranked stocks from the drug/biotech sector are Bellerophon Therapeutics, Inc. BLPH, Akero Therapeutics, Inc. AKRO and Repligen Corporation RGEN, each carrying a Zacks Rank #2 (Buy). A Republican Congress wouldnt reduce inflation. Pfizer to acquire Arena Pharmaceuticals in $6.7 billion deal - CNBC Trials have progressed to Phase III stage in which its impact on morbidity, mortality and exercise capacity is being evaluated. During Phase II OASIS trials for ulcerative colitis, patients with eczema manifestations had responded to therapy as the S1P receptor subtypes also modulate other biological responses. Pfizer Acquires Arena Pharmaceuticals To Widen Immuno-Inflammatory Disease Pipeline December 29, 2021 Premier biopharma company Pfizer has locked down a deal to acquire Arena Pharmaceuticals for $6.7 billion, an all-cash transaction that will broaden its capabilities to produce therapies for treatment of immuno-inflammation conditions such as . Pfizer To Expand Immuno-Inflammatory Pipeline With Arena Acquisition Arena Pharmaceuticals and Aristea Therapeutics Establish Collaboration That deal closed in May. Arena Pharmaceuticals, Inc. - Product Pipeline Review - 2014 Am I the worlds biggest fool? I married my husband after being together for 25 years. ARENA Pharmaceuticals is a team with a singular purpose - deliver important medicines to patients. THIS COFFEE RUN SPARKED AN IDEA TO DESIGN TRIALS WITH PATIENTS' LIVES IN MIND. All rights reserved. Today, that discovery is still the heart of the Zacks Rank. On February 27, Cantor Fitzgerald analyst Alethia Young reduced target price for Arena from $62. In a rapidly changing global market, we work with a sense of urgency every day to understand the needs of all our stakeholders, identify bold, sometimes disruptive, ideas to get medicines to patients, and relentlessly execute until it's done. Pfizer has completed its acquisition of all outstanding shares, options, and restricted stock units of Arena for $100 per share, in cash, for a total equity value of approximately $6.7 billion . Arena Pharmaceuticals, Inc. price | Arena Pharmaceuticals, Inc. Quote. All images are owned or licensed by Arena Pharmaceuticals and may not be downloaded or reproduced. PFE, Arena Pharmaceuticals and Aristea Therapeutics Establish Collaboration APD418 is currently in Phase 2 for acute heart failure. Pfizer Completes Acquisition of Arena Pharmaceuticals - Benzinga Zacks is the leading investment research firm focusing on stock research, analysis and recommendations. Arena Pharmaceuticals: Buy The Dip Ahead Of Catalyst - SeekingAlpha Twitter founder and former chief executive, Jack Dorsey, on Saturday apologized for the layoffs involving about 50% of the staff, announced by new owner, Elon Musk on Friday. Our pipeline includes four investigational medicines in eight indications and eleven ongoing or planned clinical trials. In 1978, our founder discovered the power of earnings estimate revisions to enable profitable investment decisions. Back in March 2018, Arena completed its Phase II randomized, double-blind, placebo-controlled multinational study returning positive results after which two Phase III trials were initiated, ELEVATE UC 52 and ELEVATE UC 12, two concurrent studies that will last 52 weeks with readouts expected to be released simultaneously sometime in 2021. Type a symbol or company name. THIS COFFEE RUN SPARKED AN IDEA TO DESIGN TRIALS WITH PATIENTS' LIVES IN MIND. Many patients suffering from Crohns disease are prescribed opioids to help with pain management, however this can cause further irritation to the GI tract along with a separate issue, that of addiction to the painkiller.
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